Mannitol

GI(Glucose = 100)

0^*0^*

Energy(kcal/100g)

160 kcal^*160 kcal^*

Carbs(g/100g)

100 g^*100 g^*

Sugars(g/100g)

0 g^*0 g^*

Functional benefits

• Does not promote dental caries

  21 CFR 101.80 eligible sugar alcohol when food sugars/plaque-pH criteria are met. Not an anticaries drug claim.

  FDA — 21 CFR 101.80 Health claims: noncariogenic carbohydrate sweeteners and dental caries (2024)

Cited minerals can add up to +2 on Best sweetener for everyday health — see Methods.

Risks & side effects

• Osmotic GI discomfort

  caution

  No human single-dose threshold found. In a Parkinson's trial raising oral mannitol to 18 g a day, 6 of 14 could not go higher because of GI symptoms — patients, not healthy adults. Not a medical diagnosis. Scored: −7 on Everyday Health, Diabetic-friendly and Minimally processed — no symptom-free single dose on file, so the 75th percentile of rows with one (missing is not clean).

  Linetsky et al. — Safety and tolerability, dose-escalating, double-blind trial of oral mannitol in Parkinson's disease (Front Neurol) (2022)

Not medical advice. Published recipe penalties (if any) are on Methods — not a clinical severity scale.

Notes

No extra context notes on file yet.

Notes explain what the open axis or risk labels alone can miss — not medical advice.