Allulose

GI(Glucose = 100)

0^*0^*

Energy(kcal/100g)

40 kcal^*40 kcal^*

Carbs(g/100g)

100 g^*100 g^*

Sugars(g/100g)

0 g^*0 g^*

Functional benefits

• Does not promote dental caries

  FDA labeling guidance: plaque-pH evidence — does not promote dental caries. Not a 21 CFR 101.80 health-claim listing.

  FDA — Declaration of allulose and calories from allulose (guidance) (2020)

• GLP-1 release / glucose tolerance (animal)

  Iwasaki et al. (Nat Commun): oral D-allulose raises GLP-1 and improves glucose tolerance via GLP-1R / vagal afferents in rodents. Display-only mechanism — not a human diabetes or weight-loss drug claim.

  Iwasaki et al. — D-allulose GLP-1 release and vagal afferents (Nat Commun) (2018)

Cited minerals can add up to +2 on Best sweetener for everyday health — see Methods.

Risks & side effects

• Osmotic GI discomfort at large doses

  caution

  Largest symptom-free single dose 0.4 g/kg (29 young adults, dose raised weekly); at 0.5 g/kg 13 of 29 had diarrhoea. Daily maximum 0.9 g/kg. An older trial put the symptom-free dose near 0.55 g/kg (Iida 2007, not yet checked); the lower figure is scored. Not a medical diagnosis. Scored: −3 on Everyday Health, Diabetic-friendly and Minimally processed — largest symptom-free single dose 0.4–0.6 g/kg.

  Han et al. — Gastrointestinal tolerance of D-allulose in healthy and young adults. A non-randomized controlled trial (Nutrients) (2018)

Not medical advice. Published recipe penalties (if any) are on Methods — not a clinical severity scale.

Notes

No extra context notes on file yet.

Notes explain what the open axis or risk labels alone can miss — not medical advice.